18 min read

Niacin deficiency the missing link

Niacin deficiency the missing link
Photo by julien Tromeur / Unsplash

The most censored healing protocol is that of addressing niacin deficiency in order to heal. That's a bold statement but hear me out. Niacin is vitamin B3 and is essential to convert food into energy. Dmitry Kats (PhD, MPH), says 'Being 20% deficient of niacin for a month is a bioweapon' and the form of niacin that works is full flush niacin or nicotinic acid, not niacinamide. If there is one supplement, you want on hand it is high dose full flush niacin. Niacin or vitamin B3 is a water-soluble vitamin used by the body to form the nicotinamide coenzyme, NAD+.

Of course, I am not giving medical advice but from my personal experience and all the case studies and evidence that I will present below, you make up your own mind. Google and medical sites will tell you that you get all the niacin you need from foods and don't need to supplement, and they like to recommend the wrong form of niacin and doses so low to be ineffective and caution "The supplement has been linked with liver damage, can cause hypotension and might activate a peptic ulcer. Taking niacin also might worsen allergies, gallbladder disease and symptoms of certain thyroid disorders. If you have diabetes, niacin can interfere with blood glucose control." Sounds horrific, doesn't it?

I too was put off taking niacin for a long time because of all these "warnings" but then I saw results in myself, friends, testimonials and the biggest thanks must go to Dmitry Kats for his tireless scientific approach and no bullshit outspokenness, dispelling the propaganda to bring knowledge of niacin's benefits to the world. It isn't that diet and lifestyle isn't important (because they absolutely are) but that when someone becomes so deficient in niacin due to infection, stress, medications, vaccinations, chemicals in the environment, pesticides, etc.. you need to get your niacin to a good baseline in order to properly absorb nutrients. In the absence of doing this, you will get more and more depleted, leading to oxidative stress, inflammation and disease. It is like giving a car a jump start. If the car is so depleted of energy, you can try and start it as often as you like, in the end, it's going to flatten the battery. Niacin does this for the body, and then you can continue to put the good stuff in and reverse illness.

I think the most impressive part of niacin that caught my attention was it's ability to detox the bio-weapon from the jab. That's right, it removed the nanotechnology. I was already familiar with the decades old, tried and tested work of L.Ron Hubbard Clear Body Clear Mind and the niacin/sauna detox protocol. I had been in a Smart Detox with Niacin and Infrared Sauna Facebook group for years but hadn't actually got around to trying niacin myself. I had seen people's test result come back from being able to detoxify heavy metals and because niacin breaks open fat cells, a process called lipolysis, it releases toxins allowing you to remove them from your body, with sweating accelerating the removal of toxins.  (Do not use the no-flush version, nicotinamide, because the important part of the detox is the flush.)

Yet, why didn't I try it myself? Well, I thought I didn't need to!

Sometimes, a gift horse is staring you in the face and you don't see it. Fast forward to May 2022, and being really sick with some post covid gut problem that led to heart failure of EF 15% (which is really bad), led me to go back to the drawing board and research, talk to people, and put the puzzle pieces together. There is nothing quite like having your back to the wall and looking for answers and I am glad to report that I am feeling fantastic, doing 1-2 hours physical exercise daily on top of a busy life, paying attention to nutrition as well and staying balanced. The last echocardiogram, a few months ago saw my heart function double.

Niacin is the backbone of two enzymes known as NAD and NADP which work together helping as many as 200 other energy-related enzymes do their work. The ability of your body to break down fats, carbohydrates, and proteins and use them to make energy is dependent on having adequate niacin and this energy feeds the mitochondria, your cellular "engines," the conversion of food to energy (ATP) and without adequate niacin, things just don't work.

In this current environment, not only are we exposed to the bioweapon spike protein through infection but also through vaccinated people shedding, and a host of chemicals in the environment and EMF radiation. It's well established now that unvaccinated people have had harmful changes to the blood due to close exposure to the vaccinated, as seen under a microscope (live blood analysis).

The mechanism of the bioweapon as proposed by Dmitri Kats is that it depletes niacin and messes up the gut bacteria and I think he is absolutely spot on here!

The changes to the gut lead to a whole host of post covid symptoms from hair loss, exhaustion, susceptibility to infection, digestion issues, memory and neurological problems, changes in taste and smell, relapse/activation/worsening of pre-existing or past health conditions. If one has taken pharmaceuticals like antibiotics, anti-virals, vaccinations, or are exposed to chemicals/pesticides, radiation, that further depletes niacin and once niacin falls too low, it really is an uphill struggle to get back to normal. In many cases, people will simply become more and more depleted and this leads to disease and death.

A messed up gut means that you can't properly absorb your food, leading to more and more deficiencies, further depleting stores of selenium, E, folate, b12, niacin, and leading to oxidative stress and inflammation. And while anti-oxidants like vitamin C, NAC, quercertin may seem like a good idea; they are dealing with the symptoms of the problem not the cause, which is niacin deficiency. Fix the niacin deficiency and you bring down inflammation and oxidative stress naturally. Diet alone may not be able to address niacin deficiency and the goal is to replenish niacin stores in the body, so that it is able to function optimally again and absorb the minerals, vitamins and nutrients that you need to properly function.

Without niacin, signalling is all messed up to transfer niacin and other nutrients into the body. For someone who has a minor niacin deficiency, a few doses of niacin can restore balance again. However for the severely deficient and the chronically ill, recovery will depend on dosage, the time to restore the level of depletion, individual absorption and other supplements like selenium, E, folate, b12, (b6 and b9 can be replaced with lactoferrin), protein from raw a2 milk.

For faster results, higher doses will mean resolution of issues in a week or less, according to Kats. Who also says, that people who were really sick with covid, took 500g -1000g of full flush niacin and sweat out the sickness, feeling better overnight. People often start with a low dose and continue to increase niacin over time because detox reactions can be intense.

Medications counter the effect of niacin because they deplete niacin and while quercetin, ascorbic acid, low carb eating, fasting, vitamin D etc.. all try to mimic niacin, taking niacin is a far superior option! Think of ingesting niacin as the inverse of inflammation, oxidative stress and free radical electrons.  Niacin is the exact counter of these things and cancels out the harm. It also mimics what exercise does, by producing nitric oxide and the activation of GPR109a receptors. According to Kats, "niacin happens to be the root, the prime to biology, there was no living thing existed until niacin helped it form."

With a sedentary life, niacin becomes more depleted and it follows that the increase in Alzeihmer's is due to the depletion of niacin through the consumption of medication and a sedentary life. In his research, as one ages it becomes necessary to do more exercise to counter the effect of aging and he says the need to burn energy from food consumed through exercise is required to be healthy and this is where his theory about the benefits of the niacin flush comes in, that it mimics exercise by releasing the energy from the body. It does make sense that as humans, we were not made to live a sedentary life and an excess of what Chinese medicine calls "chi" becomes harmful and too much heat leads to stagnation and disease.

Niacin was dubbed the exercise pill, by Kats because niacin mimics the benefits of exercise to overall health.

So what made Kats look into niacin for covid?

In the early days a number of observational studies found an inverse relationship between smoking and severe acute respiratory syndrome coronavirus, which later on, other studies were at pains to debunk.

It is what should have opened our eyes to the link to niacin.

"Motivation for this original investigation into specifically NA supply as COVID-19 treatment was sparked by deduction of the possibility that the counterintuitive link observed with (cigarette/tobacco-nicotine) smoking as being protective against ensuing severe acute respiratory virus 2 (SARS-CoV-2) infection may be explained by the fact that nicotine is oxidized into NA during the combustion process [1], combined with realization—through elucidation by this research—of the exclusive ability of NA (upon which the human species continues dynamically to be thoroughly deficient through diet) through its unique, intricate, endothermic biochemical processing to induce a thermodynamic flush to ultimately reverse, restore health from, and/or protect against ensuing inflammatory-induced disease" https://files.osf.io/v1/resources/uec3r/providers/osfstorage/5feadb641e6d97028f2fa29f?action=download&direct&version=1

INFORMAL DISCUSSION

( Dmitry Kats discussing niacin in lay man's terms https://t.me/uncensoredwisdom/1689 and https://t.me/uncensoredwisdom/1690  . These are really both excellent small monologues by Kats)

Long Discussion with Dmitry Kats on the Niacin Protocol and it's evolution. A lot Science Talk.

In this talk, Dmitry Kats explains that changes to the gut microbes due to covid19 infection, how it depletes butyrate in the gut, which then leads to the gut becoming permeable and this leads to opportunistic pathogenic bacteria/viruses overgrowing in the body, and hyper inflammation leading to disease.

His explanation is exactly what happened to me, that my gut bacteria had become depleted of butyrate, and my gut essentially went septic and it's interesting that I turned things around with a dose of niacin, curcumin from curry laksa soup and later on butyrate rich foods with resistant starch like cooled potatoes. https://uncensoredwisdom.com/heart-failure/ is the full story.

He says that Chapel Hill refused to publish his research on niacin to cure covid19 because they had contracts for the drug Remdesivir and contracts with Moderna.

Kats says that low GPR109a expression is associated with microbial changes in the gut that is present in all covid long haulers and if this gut change is not reversed, the gut will become more and more permeable and depleted and this will lead to a cytokine storm and then colorectal cancer. The solution is to take high dose full flush niacin, butyrate, curcummin which reverses the harm by suppressing the bad bacteria, feeding the good and restoring niacin to a good baseline in order to properly convert food to energy. This is just the first stage because nutrition is important and so many other things, which for the purposes of this article I won't go into but you can read more https://uncensoredwisdom.com/practical-tips-for-healing/

According to Kats, through his work with people who have sought out his help, restoring niacin has helped people heal from cancer, Alzeihmer's, Parkinson, dementia, long covid and many other conditions.

Dmitry Kats, PhD: From Niatonin to Niacur |
In this episode, I have Dr. Dmitry Kats, MPH, PhD. He has a PhD in epidemiology from the University of North Carolina at Chapel Hill. Many people have asked me what I think of his Niatonin protocol for COVID. And as you’ll see in this interview that has since evolved into the Niacur protocol, which…

Below is Dimtry Kats protocol. He has an online community and consultation through the website as well. Please support his research into the use of niacin. He's a high functioning autistic that is thinking outside the box here, which is exactly what we need. He is not your polished, pharmaceutical doctor with that corporate air about him. Please don't dismiss what he says.

He is focussed on the mechanism of how niacin works, not just throwing a whole heap of supplements in the mix and hoping for the best. Example: Vitamin D is dependent on butyrate for absorption, so if your butyrate is low, it's pointless taking vitamin D and similarly zinc needs niacin and when your niacin is depleted, how can zinc help you. Vitamin D can also lead to excess calcium being deposited in the body, and needs to be modulated with k2. Yet so many practitioners recommend supplements in isolation, without thought of the mechanism of absorption, healing, the other interactions/effects and individual dosages based on the current health profile of the recipient.

It is what is wrong with the whole medical studies system, because you simply cannot get identically matched subjects to do a study on and even if you did, the results would only be specific to that study group. There is also no financial incentive to research anything that cannot be patented.

He has also seen thousands of people damaged with pharmaceutical drugs, specifically the ones being recommended against covid19. I don't want to get too much into this topic for the purpose of this article, but you can perform a search with the name of the drug + neurotoxicity and you will find many, many results. All pharmaceutical drugs need to have a risk/benefit analysis and if you take or have taken pharmaceutical drugs that you need to consider yourself niacin depleted (even slightly) and restore your niacin levels and your gut health.

Protocol – HOM3OSTASIS

STUDIES

All studies are limited in scope, and don't take on individual differences, dosages, genetics, etc. I present the following, simply to highlight the importance of b vitamins and the mechanisms it influences.

"This study investigated the effects of dietary niacin on intestinal mucosal immune and physical barrier, and relative mRNA levels of signaling molecules in the intestine of young carp and concluded, our study was the first study to show that (1) niacin deficiency-decreased intestinal mucosal immune function may be partly by decreasing lysozyme and acid phosphatase activities, and complement 3 content, and hepcidin and LEAP-2 expression as well as up-regulating pro-inflammatory cytokines (TNF-α, IL-1β, IFN-γ2 and IL-8) expression and down-regulating anti-inflammatory cytokines (IL-10 and TGF-β1) which may be involved in the NF-κB pathway (including signal molecules NF-κB P65"

https://www.sciencedirect.com/science/article/abs/pii/S1050464815302734

While this study was done on carp, what is illustrating is that niacin depletion effects the intestinal mucosal immune function.

Vitamin B6 and Diabetes: Relationship and Molecular Mechanisms
Vitamin B6 is a cofactor for approximately 150 reactions that regulate the metabolism of glucose, lipids, amino acids, DNA, and neurotransmitters. In addition, it plays the role of antioxidant by counteracting the formation of reactive oxygen species ...

NIACIN FOR HEART DISEASE

Nicotinic acid is a well-known lipid-lowering agent: Nicotinic acid therapy markedly increases high-density lipoprotein (HDL) cholesterol concentrations, decreases serum lipoprotein(a) concentrations, and shifts small, dense low-density lipoprotein (LDL) particles to large, buoyant LDL particles. All of these changes in the blood lipid profile are considered cardioprotective. Low concentrations of HDL-cholesterol are one major risk factor for coronary heart disease (CHD), and an increase in HDL concentrations is associated with a reduction of that risk. https://lpi.oregonstate.edu/mic/vitamins/niacin

NIACIN FOR DIABETES

"Long-term niacin treatment resulted in insulin resistance and increased β-adrenergic responsiveness that may in part be explained by a niacin-induced downregulation of PDE3B." https://journals.physiology.org/doi/full/10.1152/ajpendo.00641.2013

"Several studies have shown that insufficient intake of vitamin B6 is associated with increased cancer risk and growing evidence indicates that diabetes patients have a higher risk of developing various types of cancer." https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146109/

IMPORTANCE OF BUTYRATE

Butyrate moderates systemic inflammation in the gut. It is the main fuel for the cells that line the gut, known as “colonocytes”, providing up to 90% of their energetic requirements. In other words, butyrate helps these cells fulfil their functions correctly, thus maintaining the integrity of the gut lining, called “mucosa” . We need an abundance of it. Exposure to pesticides, toxins, stress, anti-biotics reduce butyrate.

Kats has recently started recommending raw milk specifically with a2 protein. I think there is an even more amazing substance to use to heal the gut in combination with niacin and that is kefir. It was part of my healing journey when I recovered from heart failure in 2011-12 and went on to have a healthy pregnancy and baby at the age of 43.

KEFIR

Kefir is a fermented and probiotic-packed beverage that’s been used for thousands of years by nomadic cultures and was known for it's magical properties are real-life health benefits because it is able to heal a variety of digestive ailments and by healing the gut, other issues are also resolved. The best kefir is the homemade one that is very easy to make and all you need is some starter grains. It restores balance but to the gut, and can be used ideally with niacin. Kefir has calcium, B vitamins, K2 and other vitamins that are more absorbed due to the bacteria. https://www.yemoos.com/pages/milk-kefir-nutritional-profile

The Surprisingly Dark History of Kefir, the Fermented Milk Beverage of the Caucasus
A kidnapping is involved.
The Fascinating Origins of Milk Kefir Grains
Where does kefir come from? To reach us, this famous fermented milk has crossed the ages and many adventures. Click here to read its fascinating origins!

A very interesting thing to note is that a doctor called Dr Jeff Bradstreet was working on a lab grown milk product to reverse autism and treat disease called gcMAF. He was having great success before he mysteriously died. It's actually quite difficult to source the genuine version of this product but I include it here out of interest, because it supports the idea that if you heal the gut and restore balance to it, then you can heal the body.

Fixing niacin deficiency is an important first step, as dealing with any parasitic infection, but there are many things that are required to live a healthy life. Here are things I have learnt after recovering from heart failure.

Roadmap to healing, aging backwards and longevity
Friends, for many years I have desired to lay out a road map for healing for chronic illness but held back because there was always more to learn or unlearn. I wanted to share a perfect path that would lay out an easy route. Do x,y and z and

This is really important information that you can do more research into and share with others.

Scroll to the bottom of the article for nicotinic acid recommendations

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Nicotinic acid recommendations

Make sure you order the full flush, nicotinic acid and not the other more easily available version. Check dosage.

See https://hom3ostasis.com/protocol/ . This is the current protocol as of January 2023